Home Tools

Log in

Search Result

Search Results for " c fms in 1 "

13

Compounds

Cat No.	Product Name	Synonyms	Targets
T10643	c-Fms-IN-1		c-Fms
	c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).		c-Fms
T10894	CSF1R-IN-1		c-Fms
	CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.		c-Fms
T13194	CSF1R-IN-2		c-Fms , c-Met/HGFR , Src
	CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).		c-Fms , c-Met/HGFR , Src
T2051	SKLB4771	FLT3-IN-1,FLT3-IN-1	FLT
	SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.		FLT
T2668	JNK-IN-8	JNK Inhibitor XVI	JNK , c-Kit
	JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line.		JNK , c-Kit
T3211	Midostaurin	N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251	Others , PKC
	PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...		Others , PKC
T0097L	Pazopanib	GW786034	VEGFR , FGFR , PDGFR , c-Kit , Autophagy
	Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...		VEGFR , FGFR , PDGFR , c-Kit , Autophagy
T2624	OSI-930	OSI 930	Apoptosis , c-Fms , Raf , VEGFR , FLT , CSF-1R , Src , c-Kit
	OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
T10648	c-Fms-IN-9		c-Fms
	c-Fms-IN-9 is a c-FMS inhibitor. It inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT (IC50s: <0.01 μM and 0.1-1 μM).		c-Fms
T10645	c-Fms-IN-6		c-Fms
	c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: > 1 μM).		c-Fms
T10647	c-Fms-IN-8		CSF-1R
	c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.		CSF-1R
T79815	c-Fms-IN-14		c-Fms
	c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].		c-Fms
T10644	c-Fms-IN-10		Others
	c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, a kinase inhibitor of FMS (Colony-stimulating factor-1 receptor, CSF-1R; IC50: 2 nM) with anti-tumor activity.		Others

Compounds

Target: c-Fms, c-Met/HGFR, Src

Synonym: FLT3-IN-1,FLT3-IN-1

Synonym: JNK Inhibitor XVI

Target: JNK, c-Kit

Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251

Target: Others, PKC

Synonym: GW786034

Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy

Synonym: OSI 930

Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

TargetMol

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved.

TargetMol